Olinone ( Olinone )

Catalog No. M12666 CAS No. 1770789-37-1

Olinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	873	Get Quote
50MG	1782	Get Quote
100MG	2250	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Olinone
Note

Research use only, not for human use.
Brief Description

Olinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively.
Description

Olinone is a selective inhibitor for the BET BRD1 with Kd of 3.4/3.7/8.6 uM for BRD4-BrD1/BRD3-BrD1/BRD2-BrD1, respectively, shows high selectivity over BET BRD2 (Kd>300 uM); accelerates the progression of mouse primary oligodendrocyte progenitors toward differentiation.
Synonyms

Olinone
Pathway

Chromatin/Epigenetic
Target

Bromodomain
Recptor

Bromodomain
Research Area

——
Indication

——

Chemical Information

CAS Number

1770789-37-1
Formula Weight

299.37
Molecular Formula

C17H21N3O2
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(NCCCCN1C(CCN2)=C(C2=O)C3=C1C=CC=C3)=O
Chemical Name

N-[4-(1-Oxo-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-yl)-butyl]-acetamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Gacias M, et al. Chem Biol. 2014 Jul 17;21(7):841-54.
2. Chiang CM. Chem Biol. 2014 Jul 17;21(7):804-6.
3. Zhao L, et J Neuroinflammation. 2017 Jan 19;14(1):14.al.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks