Cart
sales@molnova.com
Home - Products - GPCR/G Protein - CGRP Receptor - Olcegepant

Olcegepant

CAS No. 204697-65-4

Olcegepant ( BIBN-4096;BIBN-4096BS;BIBN4096BS )

Catalog No. M13181 CAS No. 204697-65-4

The first small molecule selective CGRP antagonist with Ki of 14.4 nM for hCGRP.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 42 Get Quote
5MG 87 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Olcegepant
  • Note
    Research use only, not for human use.
  • Brief Description
    The first small molecule selective CGRP antagonist with Ki of 14.4 nM for hCGRP.
  • Description
    The first small molecule selective CGRP antagonist with Ki of 14.4 nM for hCGRP; inhibits the effects of CGRP, released by stimulation of the trigeminal ganglion, on facial blood flow in marmoset monkeys (1-30mg/kg, i.v.).
  • Synonyms
    BIBN-4096;BIBN-4096BS;BIBN4096BS
  • Pathway
    GPCR/G Protein
  • Target
    CGRP Receptor
  • Recptor
    CGRP Receptor
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    204697-65-4
  • Formula Weight
    869.65
  • Molecular Formula
    C38H47Br2N9O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 50 mg/mL
  • SMILES
    O=C(N1CCC(N2C(NC3=C(C=CC=C3)C2)=O)CC1)N[C@H](CC4=CC(Br)=C(O)C(Br)=C4)C(N[C@H](C(N5CCN(C6=CC=NC=C6)CC5)=O)CCCCN)=O
  • Chemical Name
    Piperazine, 1-[3,5-dibromo-N-[[4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl)-1-piperidinyl]carbonyl]-D-tyrosyl-L-lysyl]-4-(4-pyridinyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Doods H, et al. Br J Pharmacol. 2000 Feb;129(3):420-3.
2. Powell KJ, et al. Br J Pharmacol. 2000 Nov;131(5):875-84.
3. Edvinsson L, et al. Eur J Pharmacol. 2002 Jan 2;434(1-2):49-53.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Ubrogepant

    Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.

  • Atogepant

    A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine.

  • OTS514

    OTS514 is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).

Sign In Join Free