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Ubrogepant

CAS No. 1374248-77-7

Ubrogepant ( MK-1602;MK1602 )

Catalog No. M11544 CAS No. 1374248-77-7

Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ubrogepant
  • Note
    Research use only, not for human use.
  • Brief Description
    Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.
  • Description
    Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.Migraine Phase 3 Clinical
  • Synonyms
    MK-1602;MK1602
  • Pathway
    GPCR/G Protein
  • Target
    CGRP Receptor
  • Recptor
    CGRP Receptor
  • Research Area
    Neurological Disease
  • Indication
    Migraine

Chemical Information

  • CAS Number
    1374248-77-7
  • Formula Weight
    549.55
  • Molecular Formula
    C29H26F3N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=CN=C2C(C[C@@]3(C4=CC=CN=C4NC3=O)C2)=C1)N[C@@H]5C(N(CC(F)(F)F)[C@H](C)[C@H](C6=CC=CC=C6)C5)=O
  • Chemical Name
    (3'S)-1',2',5,7-Tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2'-oxospiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li CC, et al. J Clin Pharmacol. 2017 Nov 14. doi: 10.1002/jcph.1021.
2. Holland PR, et al. Neurotherapeutics. 2018 Apr;15(2):304-312.
3. Voss T, et al. Cephalalgia. 2016 Aug;36(9):887-98.
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