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OUL232

CAS No. 943119-42-4

OUL232( —— )

Catalog No. M36535 CAS No. 943119-42-4

OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 140 In Stock
10MG 211 In Stock
25MG 361 In Stock
50MG 544 In Stock
100MG 771 In Stock
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Biological Information

  • Product Name
    OUL232
  • Note
    Research use only, not for human use.
  • Brief Description
    OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.
  • Description
    OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. OUL232 is the most potent PARP10 inhibitor described to date (IC50=7.8 nM), as well as the first PARP12 inhibitor ever reported.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    PARP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    943119-42-4
  • Formula Weight
    250.28
  • Molecular Formula
    C10H10N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (199.78 mM; ultrasonic and warming and adjust pH to 2 with 1M HCl and heat to 80°C)
  • SMILES
    N=1N=C(N)N2C1SC=3C(OC)=CC=C(OC)C32
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Murthy S, et al. [1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. J Med Chem. 2023 Jan 4. ?
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