Cart
sales@molnova.com
Home - Products - Chromatin/Epigenetic - Epigenetic Reader Domain - OTX015

OTX015

CAS No. 202590-98-5

OTX015 ( HY-15743; ()-OTX015 )

Catalog No. M13154 CAS No. 202590-98-5

OTX015 is a potent BET bromodomain inhibitor with EC50 ranging from 10 to 19 nM for BRD2, BRD3, and BRD4. Phase 1.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 37 In Stock
5MG 60 In Stock
10MG 78 In Stock
25MG 138 In Stock
50MG 222 In Stock
100MG 375 In Stock
200MG 560 In Stock
500MG 893 In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    OTX015
  • Note
    Research use only, not for human use.
  • Brief Description
    OTX015 is a potent BET bromodomain inhibitor with EC50 ranging from 10 to 19 nM for BRD2, BRD3, and BRD4. Phase 1.
  • Description
    OTX015 is a potent BET bromodomain inhibitor with EC50 ranging from 10 to 19 nM for BRD2, BRD3, and BRD4. Phase 1.
  • Synonyms
    HY-15743; ()-OTX015
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    BRDs
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    202590-98-5
  • Formula Weight
    491.99
  • Molecular Formula
    C25H22ClN5O2S
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO:98 mg/mL (199.19 mM); Ethanol:98 mg/mL (199.19 mM); Water:<1 mg/mL (<1 mM)
  • SMILES
    O=C(NC1=CC=C(O)C=C1)C[C@H]2C3=NN=C(C)N3C4=C(C(C)=C(C)S4)C(C5=CC=C(Cl)C=C5)=N2
  • Chemical Name
    (S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide.

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Noel JK, et al. Mol Cancer Ther. 2013, 12, C244.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • GSK620

    GSK620 is a pan-BD2 inhibitor, which shows an anti-inflammatory phenotype in human whole blood with excellent broad selectivity, developability, and in vivo oral pharmacokinetics.

  • SGC2085 HCl

    SGC2085 is a potent and selective coactivator associated arginine methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs.

  • 653-47 hydrochloride

    653-47 hydrochloride is a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15.?

Sign In Join Free