
OTS447
CAS No. 1356943-67-3
OTS447( —— )
Catalog No. M35684 CAS No. 1356943-67-3
OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 192 | Get Quote |
![]() ![]() |
5MG | 297 | Get Quote |
![]() ![]() |
10MG | 471 | Get Quote |
![]() ![]() |
25MG | 877 | Get Quote |
![]() ![]() |
50MG | 1408 | Get Quote |
![]() ![]() |
100MG | 2142 | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameOTS447
-
NoteResearch use only, not for human use.
-
Brief DescriptionOTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .
-
DescriptionOTS447 is a potent FLT3 inhibitor with an IC50 of 21 nM (WO2012016082A1, compound 335).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetFLT
-
RecptorFLT
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1356943-67-3
-
Formula Weight466.02
-
Molecular FormulaC27H32ClN3O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 12.41 mg/mL (26.63 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)
-
SMILESCCN(CC)C1CCC(CC1)Nc1c(cnc2ccc(cc12)-c1ccc(O)c(Cl)c1)C(C)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Yo Matsuo, et al. Quinoline derivatives and melk inhibitors containing the same. WO2012016082A1.
molnova catalog



related products
-
FLT3-IN-2
FLT3-IN-2 is a FLT3 inhibitor with IC50 of < 1 μM.
-
BGB-102
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular degeneration and diseases associated with genetic disorders and malformations.
-
FLT3-IN-10
FLT3-IN-10 (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).