OSS-128167

CAS No. 887686-02-4

OSS-128167 ( OSS128167 )

Catalog No. M16419 CAS No. 887686-02-4

OSS-128167 is a novel selective, cell permeable SIRT6 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 49 In Stock
5MG 77 In Stock
10MG 107 In Stock
25MG 222 In Stock
50MG 410 In Stock
100MG 605 In Stock
500MG 1287 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    OSS-128167
  • Note
    Research use only, not for human use.
  • Brief Description
    OSS-128167 is a novel selective, cell permeable SIRT6 inhibitor.
  • Description
    OSS-128167 is a novel selective, cell permeable SIRT6 inhibitor with IC50 of 89, 1578 and 751 uM for SIRT6, SIRT1 and SIRT2, respectively; increases H3K9 acetylation and GLUT-1 expression in treated cells.
  • Synonyms
    OSS128167
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    SIRT6;SIRT2;SIRT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    887686-02-4
  • Formula Weight
    366.33
  • Molecular Formula
    C19H14N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 68 mg/mL (185.6 mM); Ethanol: <1 mg/mL; Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    C1=CC(NC(=O)C2=CC=CO2)=CC(C(=O)NC2=CC=C(O)C(C(O)=O)=C2)=C1
  • Chemical Name
    5-[[3-[(2-Furanylcarbonyl)amino]benzoyl]amino]-2-hydroxybenzoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Parenti MD, et al. J Med Chem. 2014 Jun 12;57(11):4796-804.
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