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ON1231320
CAS No. 1312471-39-8
ON1231320( GBO-006 )
Catalog No. M23471 CAS No. 1312471-39-8
ON1231320 is a Polo-like kinase 2 (PLK2) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 51 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 128 | In Stock |
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| 25MG | 259 | In Stock |
|
| 50MG | 403 | In Stock |
|
| 100MG | 592 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameON1231320
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NoteResearch use only, not for human use.
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Brief DescriptionON1231320 is a Polo-like kinase 2 (PLK2) inhibitor.
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DescriptionON1231320 is a Polo-like kinase 2 (PLK2) inhibitor.
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In VitroApoptosis Analysis Cell Line:U2OS cells Concentration:0-5 μM Incubation Time:24 hours Result:Increased the activity of Caspases 3/7 in a dose-dependent manner.
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In VivoAnimal Model:6-8 week old NCR nu/nu female mice with MDAMB-231 triple negative breast cancer cells Dosage:75 mg/kg Administration:IP; alternate days (Q2D) for 20 days Result:Resulted in significant inhibition of tumor growth (86.5%)
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SynonymsGBO-006
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PathwayCell Cycle/DNA Damage
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TargetPLK
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RecptorPLK2
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Research Area——
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Indication——
Chemical Information
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CAS Number1312471-39-8
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Formula Weight467.4
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Molecular FormulaC22H15F2N5O3S
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCN1C2=NC(=NC=C2C=C(C1=O)S(=O)(=O)C3=C(C=C(C=C3)F)F)NC4=CC5=C(C=C4)NC=C5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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