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O-Nornuciferine

CAS No. 3153-55-7

O-Nornuciferine( —— )

Catalog No. M24249 CAS No. 3153-55-7

O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    O-Nornuciferine
  • Note
    Research use only, not for human use.
  • Brief Description
    O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
  • Description
    O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
  • In Vitro
    O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells. O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    hERG
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3153-55-7
  • Formula Weight
    281.35
  • Molecular Formula
    C18H19NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (177.71 mM)
  • SMILES
    CN(CC1)[C@H](Cc(cccc2)c2-c2c3OC)c2c1cc3O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Human Ether-??-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements.J Agric Food Chem. 2015 Jun 17;63(23):5634-9.
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