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Nimbolide
CAS No. 25990-37-8
Nimbolide ( —— )
Catalog No. M24163 CAS No. 25990-37-8
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 205 | In Stock |
|
| 10MG | 357 | In Stock |
|
| 25MG | 597 | In Stock |
|
| 50MG | 851 | In Stock |
|
| 100MG | 1152 | In Stock |
|
| 500MG | 2313 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNimbolide
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NoteResearch use only, not for human use.
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Brief DescriptionNimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways.
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DescriptionNimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica L).
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis;CDK4;CDK6;NF-κB
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Research Area——
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Indication——
Chemical Information
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CAS Number25990-37-8
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Formula Weight466.5
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Molecular FormulaC27H30O7
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@]12[C@@]3([H])[C@](OC([C@@]3(C=CC2=O)C)=O)([H])[C@]4([H])[C@]([C@@H]1CC(OC)=O)(C5=C(C)[C@@](C6=COC=C6)([H])C[C@@]5([H])O4)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bodduluru LN, et al. Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms. Toxicol In Vitro. 2014 Aug;28(5):1026-35.
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