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Nilofabicin

CAS No. 934628-27-0

Nilofabicin( CG-400549 | CG 400549 | CG400549 | CG-0549 | CG 0549 | CG0549 | )

Catalog No. M27115 CAS No. 934628-27-0

Nilofabicin is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated acute.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Nilofabicin
  • Note
    Research use only, not for human use.
  • Brief Description
    Nilofabicin is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated acute.
  • Description
    Nilofabicin is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated acute. (In Vitro):Nilofabicin had an MIC90 of 0.5 μg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin. Among 203 strains of Staphylococcus aureus, the MICs of Nilofabicin were 0.06 to 1.0 μg/ml, with MIC(50) and MIC(90) values of 0.25 μg/ml each. All strains were susceptible to linezolid and quinupristin-dalfopristin (MICs, 0.25 to 2.0 μg/ml).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CG-400549 | CG 400549 | CG400549 | CG-0549 | CG 0549 | CG0549 |
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Prostacyclin receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    934628-27-0
  • Formula Weight
    340.44
  • Molecular Formula
    C19H20N2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (293.74 mM)
  • SMILES
    Cc1c(N)cccc1Cn1ccc(OCCc2cccs2)cc1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bexis S, et, al. Vascular actions of the prostacyclin receptor antagonist BAY 73-1449 in the portal hypertensive rat. Eur J Pharmacol. 2008 Aug 20;590(1-3):322-6.
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