Cart
sales@molnova.com
Necrostatin-7
CAS No. 351062-08-3
Necrostatin-7( —— )
Catalog No. M34110 CAS No. 351062-08-3
Necrostatin-7 (Necrostatin 7) is an inhibitor of necrotic apoptosis with cardioprotective effects, inhibits RANK-NFATc1 signaling, and attenuates macrophage differentiation into osteoblasts.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 56 | Get Quote |
|
| 5MG | 81 | Get Quote |
|
| 10MG | 138 | Get Quote |
|
| 25MG | 270 | Get Quote |
|
| 50MG | 441 | Get Quote |
|
| 100MG | 691 | Get Quote |
|
| 200MG | 888 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNecrostatin-7
-
NoteResearch use only, not for human use.
-
Brief DescriptionNecrostatin-7 (Necrostatin 7) is an inhibitor of necrotic apoptosis with cardioprotective effects, inhibits RANK-NFATc1 signaling, and attenuates macrophage differentiation into osteoblasts.
-
DescriptionNecrotatin-7 (Nec-7) is a potent necroptosis inhibitor with an EC50 of 10.6 μM. Necrotatin-7 does not inhibit recombinant RIP1 kinase.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number351062-08-3
-
Formula Weight371.41
-
Molecular FormulaC16H10FN5OS2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C1C(SC(=N)N1C2=NC=CS2)=CC3=CNN=C3C=4C=CC(F)=CC4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Weihong Zheng, et al. Structure-activity relationship study of a novel necroptosis inhibitor, necrostatin-7. Bioorg Med Chem Lett. 2008 Sep 15;18(18):4932-5.?
molnova catalog
related products
-
Flurochloridone
Flurochloridone is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.
-
Epibrassinolide
Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids is a natural brassinosteroid (BR) derivative is a plant regulator with a similar structure to mammalian steroids.
-
VAS 3947
VAS 3947 is a specific inhibitor of NADPH oxidase (NOX).VAS 3947 has a potent anti-platelet effect, inducing apoptosis through UPR activation, mainly due to protein aggregation and misfolding, independent of anti-NOX activity.
