Navuridine

CAS No. 84472-85-5

Navuridine( AZdU | AzUrd | CS-87 | 3'-Azido-2',3'-dideoxyuridine | CS 87 | AZddU )

Catalog No. M27413 CAS No. 84472-85-5

Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 61 Get Quote
10MG 106 Get Quote
25MG 222 Get Quote
50MG 353 Get Quote
100MG 533 Get Quote
500MG 1152 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Navuridine
  • Note
    Research use only, not for human use.
  • Brief Description
    Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.
  • Description
    Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.
  • In Vitro
    ——
  • In Vivo
    Pharmacokinetic Parameters of 3′-Azido-2′,3′-dideoxyuridine in male Sprague-Dawley rats. Animal Model:Adult male Sprague-Dawley rats (300-400 g)Dosage:25, 100 mg/kg Administration:Intravenous bolus injection or oral gavage (Pharmacokinetic Analysis)Result:The oral bioavailability estimates of 3′-Azido-2′,3′-dideoxyuridine at doses of 25 and 100 mg/kg averaged 53%.
  • Synonyms
    AZdU | AzUrd | CS-87 | 3'-Azido-2',3'-dideoxyuridine | CS 87 | AZddU
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    84472-85-5
  • Formula Weight
    253.218
  • Molecular Formula
    C9H11N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (987.32 mM)
  • SMILES
    OC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])n1ccc(=O)[nH]c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fang Liu, et al. N-3-oxo-octanoyl-homoserine lactone-mediated priming of resistance to Pseudomonas syringae requires the salicylic acid signaling pathway in Arabidopsis thaliana. BMC Plant Biol. 2020 Jan 28;20(1):38.
molnova catalog
related products
  • HAR-171

    HAR-171 is a small molecule gp120-CD40 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus.

  • BMS-955176

    BMS-955176 (GSK-3532795) is a second-generation HIV-1 maturation inhibitor that exhibits potent activity (EC50=3.9±3.4 nM) against a library (n=87) of gag/pr recombinant viruses.

  • AzddMeC

    AzddMeC (Az-Dcme) is a nucleoside analog with antiviral activity and is an orally active and selective inhibitor of HIV-1 reverse transcriptase and HIV-1 replication.