Naringenin

Research use only, not for human use.

Naringenin is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA.

Naringenin is a bioflavonoid drug potentially for the treatment of HCV infection. has antioxidant and chelating effects in the liver. Naringenin significantly suppressed UVB-induced extracellular signal-regulated kinase 2 (ERK2) activity and subsequently attenuated UVB-induced phosphorylation of p90(RSK) by competitively binding with ATP. Naringenin exerts potent anti-photoaging effects by suppressing ERK2 activity and decreasing FRA1 stability, followed by down-regulation of AP-1 transactivation and MMP-1 expression. Naringenin blocks TGF-β1 trafficking from the trans-Golgi network by suppressing PKC activity, resulting in a reduction of TGF-β1 secretion from breast cancer cells.

Naringenin; NSC 11855; NSC-11855; NSC11855

Others

Other Targets

CYP1A2

Inflammation/Immunology

——

480-41-1

272.26

C15H12O5

98%

DMSO : ≥ 50 mg/mL; 183.65 mM

C1[C@H](Oc2cc(cc(c2C1=O)O)O)c1ccc(cc1)O

(S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

(-20℃)

With Ice Pack

≥ 2 years