Naphthazarin

CAS No. 475-38-7

Naphthazarin( DHNQ,5,8-Dihydroxy-1,4-naphthoquinone )

Catalog No. M22399 CAS No. 475-38-7

Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG 57 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Naphthazarin
  • Note
    Research use only, not for human use.
  • Brief Description
    Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation.
  • Description
    Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. It triggers apoptosis and has anti-tumor effects.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    DHNQ,5,8-Dihydroxy-1,4-naphthoquinone
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    475-38-7
  • Formula Weight
    190.15
  • Molecular Formula
    C10H6O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Oc1ccc(O)c2C(=O)C=CC(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):369-74.
molnova catalog
related products
  • SF5

    SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.

  • CCCI-01

    CCCI-01(Centrosome Clustering Chemical Inhibitor-01) is a centrosome cluster inhibitor. CCCI-01 has anticancer activity, induces apoptosis, and can be used in the study of non-cross-resistant anticancer compounds that block centrosome clustering.

  • Bigelovin

    Bigelovin is a selective retinoid X receptor α agonist.?Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a potent cytotoxic sesquiterpene lactone from Inula sp.