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NXY-059

CAS No. 168021-79-2

NXY-059( NXY 059 | NXY059 | Disufenton sodium )

Catalog No. M12566 CAS No. 168021-79-2

NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NXY-059
  • Note
    Research use only, not for human use.
  • Brief Description
    NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo.
  • Description
    NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo; exhibits a substantial protective effect, lessening the disability caused by an experimentally induced stroke in a primate species, shows significantly decreased neurological impairment in rat model of hemorrhagic stroke.Stroke Phase 3 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NXY 059 | NXY059 | Disufenton sodium
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Neurological Disease
  • Indication
    Stroke

Chemical Information

  • CAS Number
    168021-79-2
  • Formula Weight
    381.3329
  • Molecular Formula
    C11H13NNa2O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC(C)(C)[N+](=CC1=C(C=C(C=C1)S(=O)(=O)[O-])S(=O)(=O)[O-])[O-].[Na+].[Na+]
  • Chemical Name
    1,3-Benzenedisulfonic acid, 4-[[(1,1-dimethylethyl)oxidoimino]methyl]-, sodium salt (1:2)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Marshall JW, et al. Stroke. 2001 Jan;32(1):190-8. 2. Kuroda S, et al. J Cereb Blood Flow Metab. 1999 Jul;19(7):778-87. 3. Peeling J, et al. Neuropharmacology. 2001 Mar;40(3):433-9. 4. Sydserff SG, et al. Br J Pharmacol. 2002 Jan;135(1):103-12.
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