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NVP-CGM097
CAS No. 1313363-54-0
NVP-CGM097 ( CGM097 )
Catalog No. M23472 CAS No. 1313363-54-0
NVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 105 | In Stock |
|
| 5MG | 195 | In Stock |
|
| 10MG | 323 | In Stock |
|
| 25MG | 534 | In Stock |
|
| 50MG | 777 | In Stock |
|
| 100MG | 1071 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNVP-CGM097
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NoteResearch use only, not for human use.
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Brief DescriptionNVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).
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DescriptionNVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).
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SynonymsCGM097
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PathwayOthers
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TargetOther Targets
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RecptorE1/E2/E3 Enzyme;MDM2
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Research Area——
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Indication——
Chemical Information
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CAS Number1313363-54-0
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Formula Weight659.3
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Molecular FormulaC38H47ClN4O4
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Purity>98% (HPLC)
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SolubilityDMSO:48 mg/mL (72.81 mM);Water:Insoluble
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SMILESO=C1N(C2=CC=C(N(C)C[C@H]3CC[C@H](N4CC(N(C)CC4)=O)CC3)C=C2)[C@@H](C5=CC=C(Cl)C=C5)C6=C(C=C(OC)C(OC(C)C)=C6)C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Holzer P, et al. Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors. J Med Chem. 2015 Aug 27;58(16):6348-58
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