NSC87877 ( —— )

Catalog No. M18830 CAS No. 56932-43-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

NSC87877
Note

Research use only, not for human use.
Brief Description

NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively.
Description

NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

SHP-2；SHP-1
Research Area

Neurological Disease
Indication

——

CAS Number

56932-43-5
Formula Weight

503.42
Molecular Formula

C19H13N3O7S2·2Na
Purity

98%
Solubility

——
SMILES

C1=CC2=C(C(=O)/C(=N/NC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)[O-])/C=C2S(=O)(=O)[O-])N=C1.[Na+].[Na+]
Chemical Name

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