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NRC-2694

CAS No. 936446-61-6

NRC-2694 ( —— )

Catalog No. M26774 CAS No. 936446-61-6

NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NRC-2694
  • Note
    Research use only, not for human use.
  • Brief Description
    NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.
  • Description
    NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.(In Vitro):NRC-2694 (80 ng) induce comparable inhibition of EGFR expression.(In Vivo):NRC-2694 (10 mg/kg) regresses the tumor in mice. The maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (p.o.), in toxicity studies .
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    Influenza virus
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    936446-61-6
  • Formula Weight
    418.5
  • Molecular Formula
    C24H26N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCCN1CCOCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.J V Tuttle, et al. Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents. J Med Chem
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