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NOS1-IN-1

CAS No. 357965-99-2

NOS1-IN-1( —— )

Catalog No. M34975 CAS No. 357965-99-2

NOS1-IN-1（nNOS Inhibitor I） is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 221 Get Quote
10MG 333 Get Quote
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Biological Information

  • Product Name
    NOS1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    NOS1-IN-1（nNOS Inhibitor I） is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).
  • Description
    NOS1-IN-1 is a selective and cell-permeable nNOS inhibitor with a Ki of 120 nM. NOS1-IN-1 exhibits 2617-fold and 325-fold selectivity over eNOS (Ki=39 μM) and iNOS (Ki=325 μM) , respectively. NOS1-IN-1 can be used for the research of neurological disease, including cerebral palsy (CP).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NOS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    357965-99-2
  • Formula Weight
    589.37
  • Molecular Formula
    C14H24F9N7O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(C(F)(F)F)=O.NCCNC[C@@H](N)CCCNC(N[N+]([O-])=O)=N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. J M Hah, et al. Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase. J Med Chem. 2001 Aug 2;44(16):2667-70.?
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