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Camstatin

CAS No. 1002295-95-5

Camstatin( —— )

Catalog No. M30721 CAS No. 1002295-95-5

An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Camstatin
  • Note
    Research use only, not for human use.
  • Brief Description
    An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.
  • Description
    An analog of PEP-19 with enhanced binding to and antagonism of calmodulin.
  • In Vitro
    Camstatin is a synthetic peptide encompassing the minimal IQ motif of PEP-19 that binds apoCaM and inhibits the activities of the CaM-dependent enzymes neuronal nitric oxide synthase (nNOS) and CaM-kinase II.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1002295-95-5
  • Formula Weight
    2760.19
  • Molecular Formula
    C122H203N39O34
  • Purity
    >98% (HPLC)
  • Solubility
    water:1 mg/mL
  • SMILES
    [H]N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(N)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Slemmon et al (1996) CamSTAT are peptide antagonists of calumodulin based upon a conserved structural motif in PEP-19, a neurogranin and neuromodulin J.Biol.Chem. 271 15911 PMID:
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