NMT-IN-1

CAS No. 326879-46-3

NMT-IN-1( —— )

Catalog No. M36077 CAS No. 326879-46-3

NMT-IN-1 is a potent inhibitor of N-nutyltransferase (NMT), with IC50 of 31μM for TbNMT and 66μM for hNMT. NMT-IN-1 is a potential compound for the treatment of African trypanosomiasis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 239 In Stock
5MG 352 In Stock
10MG 500 In Stock
25MG 707 In Stock
50MG 966 In Stock
100MG 1269 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    NMT-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    NMT-IN-1 is a potent inhibitor of N-nutyltransferase (NMT), with IC50 of 31μM for TbNMT and 66μM for hNMT. NMT-IN-1 is a potential compound for the treatment of African trypanosomiasis.
  • Description
    NMT-IN-1 (compound 9) is a potent N-Myristoyltransferase (NMT) Inhibitor with IC50 values of 31 and 66 μM for TbNMT and hNMT, respectively. NMT-IN-1 can be used in research of african trypanosomiasis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    326879-46-3
  • Formula Weight
    270.35
  • Molecular Formula
    C15H14N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N1C(SCC1=O)C2=CC=CC=C2)C3=CC=CC=N3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Spinks D, et, al. Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode. ChemMedChem. 2015 Nov;10(11):1821-36.?
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