Desmethoxy yangonin
CAS No. 15345-89-8
Desmethoxy yangonin( Demethoxyyangonin | 5,6-Dehydrokavain )
Catalog No. M18071 CAS No. 15345-89-8
Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 128 | In Stock |
|
| 10MG | 178 | In Stock |
|
| 25MG | 313 | In Stock |
|
| 50MG | 466 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDesmethoxy yangonin
-
NoteResearch use only, not for human use.
-
Brief DescriptionDesmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.
-
DescriptionDesmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. The induction of CYP3A23 by dihydromethysticin and Desmethoxy yangonin involves transcription activation, probably through a PXR-independent or PXR-involved indirect mechanism.
-
In Vitro——
-
In Vivo——
-
SynonymsDemethoxyyangonin | 5,6-Dehydrokavain
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number15345-89-8
-
Formula Weight228.24
-
Molecular FormulaC14H12O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 14.29 mg/mL (62.61 mM)
-
SMILESCOC1=CC(=O)OC(=C1)C=CC2=CC=CC=C2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
2-Methylhexanoic aci...
2-Methylhexanoic acid is a flavouring ingredient.
-
DS-1040 tosylate hyd...
DS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.
-
PBIT
PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes . PBIT, which inhibits JARID1B with an IC50 of about 3 μm in vitro.
Cart
sales@molnova.com