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NLRP3-IN-13
CAS No. 1704638-35-6
NLRP3-IN-13( —— )
Catalog No. M36488 CAS No. 1704638-35-6
NLRP3-IN-13 is a selective NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | In Stock |
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| 5MG | 117 | In Stock |
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| 10MG | 188 | In Stock |
|
| 25MG | 419 | In Stock |
|
| 50MG | 634 | In Stock |
|
| 100MG | 981 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNLRP3-IN-13
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NoteResearch use only, not for human use.
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Brief DescriptionNLRP3-IN-13 is a selective NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.
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DescriptionNLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayNF-κB
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TargetNOD
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RecptorNOD
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Research Area——
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Indication——
Chemical Information
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CAS Number1704638-35-6
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Formula Weight365.41
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Molecular FormulaC19H15N3O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (136.83 mM; Ultrasonic )
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SMILESO=C1OC=2C=CC=CC2N1CC(=O)NCC3=CN=CC(=C3)C4=CSC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Devita Robert, et al. Benzoxazolones as inhibitors of inflammasomes and their preparation. Patent. WO2022187804.
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