Cart
sales@molnova.com
NLRP3-IN-11
CAS No. 2769040-91-5
NLRP3-IN-11( —— )
Catalog No. M35514 CAS No. 2769040-91-5
NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 103 | Get Quote |
|
| 10MG | 150 | Get Quote |
|
| 25MG | 245 | Get Quote |
|
| 50MG | 363 | Get Quote |
|
| 100MG | 528 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNLRP3-IN-11
-
NoteResearch use only, not for human use.
-
Brief DescriptionNLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
-
DescriptionNLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases.
-
In VitroNLRP3-IN-11 has biological activity with an IC50 value of <0.3 μM in human PBMC NLRP3 assay.
-
In Vivo——
-
Synonyms——
-
PathwayNF-κB
-
TargetNOD
-
RecptorNOD
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2769040-91-5
-
Formula Weight344.8
-
Molecular FormulaC17H17ClN4O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (362.53 mM; Ultrasonic )
-
SMILESN(CC(C)(C)O)C=1C2=C(C(=NN1)C3=C(O)C=C(Cl)C=C3)C=CN=C2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1.
molnova catalog
related products
-
NOD-IN-1
A potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.
-
Lobeglitazone Sulfat...
Lobeglitazone Sulfate（CKD-501 Sulfate） is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2 diabetes mellitus (T2DM).
-
ADS032
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β production, and can be used to study respiratory inflammation or infection.
