Cart
sales@molnova.com
NBC19
CAS No. 2068818-75-5
NBC19( NBC 19 )
Catalog No. M13217 CAS No. 2068818-75-5
NBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 977 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNBC19
-
NoteResearch use only, not for human use.
-
Brief DescriptionNBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.
-
DescriptionNBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.
-
In Vitro——
-
In Vivo——
-
SynonymsNBC 19
-
PathwayNF-κB
-
TargetNOD
-
RecptorNOD
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2068818-75-5
-
Formula Weight491.644
-
Molecular FormulaC24H26BCl3N2O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name1-(6-(cyclohexylamino)-2,2-diphenyl-4-(trichloromethyl)-2,3-dihydro-1l3,3,2l4-oxazaborinin-5-yl)ethan-1-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Redondo-Castro E, et al. Sci Rep. 2018 Apr 4;8(1):5667.
2. Baldwin AG, et al. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5.
molnova catalog
related products
-
NP3-146
NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.
-
MCC950 sodium
MCC950 (CP-456773) is a potent, selective, small-molecule inhibitor of NLRP3 inflammasome with IC50 of 7.5 and 8.1 nM in BMDM and HMDM, respectively.
-
Molsidomine
Molsidomine is an orally active, long acting vasodilating drug, metabolized in the liver to the active metabolite linsidomine.
