SQ-22536

CAS No. 17318-31-9

SQ-22536 ( SQ22536 )

Catalog No. M12628 CAS No. 17318-31-9

A potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 42 In Stock
10MG 65 In Stock
25MG 147 In Stock
50MG 260 In Stock
100MG 447 In Stock
200MG 651 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SQ-22536
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM.
  • Description
    A potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM; abolishes the iloprost-induced elevation in cyclic AMP while having no significant effect on relaxation in isolated guinea-pig aorta.
  • Synonyms
    SQ22536
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Adenylate Cyclase
  • Recptor
    adenylate cyclase
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    17318-31-9
  • Formula Weight
    205.22
  • Molecular Formula
    C9H11N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 29 mg/mL
  • SMILES
    NC1=C2N=CN(C3OCCC3)C2=NC=N1
  • Chemical Name
    9H-Purin-6-amine, 9-(tetrahydro-2-furanyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fabbri E, et al. J Enzyme Inhib. 1991;5(2):87-98.
2. Hourani SM, et al. Br J Pharmacol. 2001 Jul;133(6):833-40.
3. Turcato S, et al. Br J Pharmacol. 1999 Feb;126(4):845-7.
molnova catalog
related products
  • LRE1

    A novel potent, specific and allosteric soluble adenylyl cyclase (sAC) inhibitor with IC50 of 3.3 uM in RF-MSS assays.

  • NB 001

    A potent, relatively selective and orally active adenylyl cyclase 1 (AC1) inhibitor with IC50 of 10 uM (cAMP production inhibition).

  • TIP 39, Tuberoinfund...

    This is a tuberoinfundibular neuropeptide and parathyroid hormone 2(PTH 2)-receptor agonist from hypothalmus. Synthetic TIP39 activates human and rat PTH2 receptors.