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Home - Products - Metabolic Enzyme/Protease - Adenylate Cyclase - SQ-22536

SQ-22536

CAS No. 17318-31-9

SQ-22536 ( SQ22536 )

Catalog No. M12628 CAS No. 17318-31-9

A potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SQ-22536
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM.
  • Description
    A potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM; abolishes the iloprost-induced elevation in cyclic AMP while having no significant effect on relaxation in isolated guinea-pig aorta.
  • Synonyms
    SQ22536
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Adenylate Cyclase
  • Recptor
    adenylate cyclase
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    17318-31-9
  • Formula Weight
    205.22
  • Molecular Formula
    C9H11N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 29 mg/mL
  • SMILES
    NC1=C2N=CN(C3OCCC3)C2=NC=N1
  • Chemical Name
    9H-Purin-6-amine, 9-(tetrahydro-2-furanyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fabbri E, et al. J Enzyme Inhib. 1991;5(2):87-98.
2. Hourani SM, et al. Br J Pharmacol. 2001 Jul;133(6):833-40.
3. Turcato S, et al. Br J Pharmacol. 1999 Feb;126(4):845-7.
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