Cart
sales@molnova.com
NIBR-17
CAS No. 944396-88-7
NIBR-17 ( —— )
Catalog No. M27568 CAS No. 944396-88-7
NIBR-17 is a pan class I PI3K inhibitor. NIBR-17 inhibits PI3KKα, PI3KKβ, PI3KKγ, and PI3KKδ with IC50 of 1 nM, 9.2 nM, 9 nM, and 20 nM respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 352 | Get Quote |
|
| 10MG | 524 | Get Quote |
|
| 25MG | 839 | Get Quote |
|
| 50MG | 1143 | Get Quote |
|
| 100MG | 1521 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNIBR-17
-
NoteResearch use only, not for human use.
-
Brief DescriptionNIBR-17 is a pan class I PI3K inhibitor. NIBR-17 inhibits PI3KKα, PI3KKβ, PI3KKγ, and PI3KKδ with IC50 of 1 nM, 9.2 nM, 9 nM, and 20 nM respectively.
-
DescriptionNIBR-17 is a pan class I PI3K inhibitor. NIBR-17 inhibits PI3KKα, PI3KKβ, PI3KKγ, and PI3KKδ with IC50 of 1 nM, 9.2 nM, 9 nM, and 20 nM respectively.
-
Synonyms——
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPI3K
-
RecptorDEPTOR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number944396-88-7
-
Formula Weight380.4
-
Molecular FormulaC18H20N8O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCOc(cc1)ncc1Nc1cc(-c2cnc(N)nc2)nc(N2CCOCC2)n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hou Y, et al. Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment. J Med Chem. 2021 Oct 28;64(20):14942-14954.
molnova catalog
related products
-
AZD8835
AZD8835 (AZD-8835) is a potent, selective inhibitor of PI3Kα and PI3Kδ with IC50 of 6.2 and 5.7 nM.
-
Trihexyphenidyl hydr...
Trihexyphenidyl hydrochloride is an antiparkinsonian agent of the antimuscarinic class.
-
Tectorigenin
Tectorigenin is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing.
