NH2-C2-NH-Boc
CAS No. 57260-73-8
NH2-C2-NH-Boc ( PROTAC Linker 22 )
Catalog No. M22435 CAS No. 57260-73-8
NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | 37 | In Stock |
|
500MG | 43 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNH2-C2-NH-Boc
-
NoteResearch use only, not for human use.
-
Brief DescriptionNH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
DescriptionNH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
SynonymsPROTAC Linker 22
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorAlkyl-Chain
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number57260-73-8
-
Formula Weight160.21
-
Molecular FormulaC7H16N2O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC(C)(C)OC(=O)NCCN
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
molnova catalog
related products
-
m-PEG7-4-nitrophenyl...
m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
TL13-12
TL13-12 is a novel Anaplastic Lymphoma Kinase (ALK)-PROTAC developed through conjugation of TAE684 and the cereblon ligand pomalidomide.
-
Bromo-PEG2-CH2-Boc
Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.