
5-Ethynyl-2-deoxyuridine
CAS No. 61135-33-9
5-Ethynyl-2-deoxyuridine( —— )
Catalog No. M33539 CAS No. 61135-33-9
5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine used to monitor de novo DNA synthesis through click chemistry and serves as an alkyl chain-based PROTAC linker for synthesizing PROTACs.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
50MG | 30 | Get Quote |
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100MG | 48 | Get Quote |
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500MG | 156 | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product Name5-Ethynyl-2-deoxyuridine
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NoteResearch use only, not for human use.
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Brief Description5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine used to monitor de novo DNA synthesis through click chemistry and serves as an alkyl chain-based PROTAC linker for synthesizing PROTACs.
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Description5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation. 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In Vitro——
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In VivoAnimal Model:Two month old female miceDosage:10, 20, 50, 100 or 200 mg/kg Administration:Single injection; intraperitoneally; 4 hours after EdU injection, brains were processed for EdU staining.Result:EdU positive cell numbers slightly increased in a dose-dependent manner both in control and running mice.
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number61135-33-9
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Formula Weight252.22
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Molecular FormulaC11H12N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (198.24 mM; Ultrasonic )H2O : 25 mg/mL (99.12 mM; Ultrasonic)
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SMILESOC[C@H]1O[C@H](C[C@@H]1O)n1cc(C#C)c(=O)[nH]c1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chenbo Zeng, et al. Evaluation of 5-ethynyl-2'-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system. Brain Res. 2010 Mar 10;1319:21-32.?
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