NG-52 ( Compound 52 )

Catalog No. M13385 CAS No. 212779-48-1

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HPLC

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Product Name

NG-52
Note

Research use only, not for human use.
Brief Description

NG 52 (Compound 52 ) is a potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase.
Description

NG 52 (Compound 52 ) is a potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC50 = 7 μM).
Synonyms

Compound 52
Pathway

Angiogenesis
Target

CDK
Recptor

Cdc28p
Research Area

Cancer
Indication

——

CAS Number

212779-48-1
Formula Weight

346.81
Molecular Formula

C16H19ClN6O
Purity

>98%(HPLC)
Solubility

DMSO: > 100mM
SMILES

CC(C)N1C2=NC(NCCO)=NC(NC3=CC=CC(Cl)=C3)=C2N=C1
Chemical Name

2-((6-((3-chlorophenyl)amino)-9-isopropyl-9H-purin-2-yl)amino)ethan-1-ol

1.ray NS, et al. Science. 1998 Jul 24;281(5376):533-8.

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