Cart
sales@molnova.com
NF-1819
CAS No. 1881244-28-5
NF-1819( —— )
Catalog No. M34346 CAS No. 1881244-28-5
NF-1819 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 55 | Get Quote |
|
| 10MG | 92 | Get Quote |
|
| 25MG | 182 | Get Quote |
|
| 50MG | 329 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNF-1819
-
NoteResearch use only, not for human use.
-
Brief DescriptionNF-1819 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor.
-
DescriptionMGL-IN-1 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. MGL-IN-1 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. MGL-IN-1 displays high membrane permeability and brain penetrant.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetLipase
-
RecptorLipase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1881244-28-5
-
Formula Weight463.46
-
Molecular FormulaC24H22FN5O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 62.5 mg/mL (134.86 mM; Ultrasonic )
-
SMILES[H][C@@]1(N(C2CCN(CC2)C(=O)n2cncn2)C(=O)[C@]1([H])c1ccc(F)cc1)c1ccc2OCOc2c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Brindisi M, et al. Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. J Med Chem. 2016 Mar 24;59(6):2612-32. ?
molnova catalog
related products
-
JW 642
JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL)
-
MAGL-IN-4
MAGL-IN-4 is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
-
Cravatt Reagent
Cravatt Reagent is a potent and selective MAGL inhibitor. Cravatt Reagent inhibits MAGL (IC50 = 9.1 nM). MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.
