NF-1819( —— )

Catalog No. M34346 CAS No. 1881244-28-5

NF-1819 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	55	Get Quote
10MG	92	Get Quote
25MG	182	Get Quote
50MG	329	Get Quote
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Biological Information

Product Name

NF-1819
Note

Research use only, not for human use.
Brief Description

NF-1819 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor.
Description

MGL-IN-1 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. MGL-IN-1 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. MGL-IN-1 displays high membrane permeability and brain penetrant.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Lipase
Recptor

Lipase
Research Area

——
Indication

——

Chemical Information

CAS Number

1881244-28-5
Formula Weight

463.46
Molecular Formula

C24H22FN5O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (134.86 mM; Ultrasonic )
SMILES

[H][C@@]1(N(C2CCN(CC2)C(=O)n2cncn2)C(=O)[C@]1([H])c1ccc(F)cc1)c1ccc2OCOc2c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Brindisi M, et al. Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. J Med Chem. 2016 Mar 24;59(6):2612-32. ?

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