JW 642( —— )

Catalog No. M26726 CAS No. 1416133-89-5

JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL)

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	31	Get Quote
10MG	50	Get Quote
25MG	98	Get Quote
50MG	177	Get Quote
100MG	332	Get Quote
200MG	494	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

JW 642
Note

Research use only, not for human use.
Brief Description

JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL)
Description

JW 642 is an effective inhibitor of monoacylglycerol lipase (MAGL) (IC50: 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively).(In Vitro):MAGL inhibitor JW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s: 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively).
In Vitro

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In Vivo

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Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Lipase
Recptor

HPPD
Research Area

——
Indication

——

Chemical Information

CAS Number

1416133-89-5
Formula Weight

462.392
Molecular Formula

C21H20F6N2O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 100 mg/mL (216.27 mM)
SMILES

FC(F)(F)C(OC(=O)N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Rocaboy-Faquet E, et al. A novel amperometric biosensor for ?-triketone herbicides based on hydroxyphenylpyruvatedioxygenase inhibition: A case study for sulcotrione. Talanta. 2016;146:510-6.

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