TRPM4-IN-1
CAS No. 351424-20-9
TRPM4-IN-1 ( CBA; 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid )
Catalog No. M24301 CAS No. 351424-20-9
TRPM4-IN-1 is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 34 | In Stock |
|
10MG | 55 | In Stock |
|
25MG | 120 | In Stock |
|
50MG | 203 | In Stock |
|
100MG | 327 | In Stock |
|
200MG | 476 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTRPM4-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionTRPM4-IN-1 is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
-
DescriptionTRPM4-IN-1 is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.
-
SynonymsCBA; 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
-
PathwayMembrane Transporter/Ion Channel
-
TargetTRP/TRPV Channel
-
RecptorTRPM4
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number351424-20-9
-
Formula Weight340.2
-
Molecular FormulaC15H11Cl2NO4
-
Purity>98% (HPLC)
-
SolubilityDMSO:80mg/ml(235.18mM; need ultrasonic)
-
SMILESOC(c(ccc(Cl)c1)c1NC(COc(cccc1)c1Cl)=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ozhathil L C , Delalande C , Bianchi B , et al. Identification of potent and selective small molecule inhibitors of the cation channel TRPM4[J]. British Journal of Pharmacology, 2018.
molnova catalog
related products
-
Pyr10
Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells (IC50: 0.72 μM) (IC50 of 13.08 μM for store-operated Ca2+ entry in BRL-2H3 cells) .
-
Olvanil
Olvanil is a vanilloid receptor agonist with EC50 of 0.7nM.
-
A-967079
A potent, selective TRPA1 channel blocker with IC50 of 51 nM and 101 nM for hTRPA1 and rTRPA1, respectively.