N-Boc-PEG5-bromide

CAS No. 1392499-32-9

N-Boc-PEG5-bromide ( —— )

Catalog No. M26767 CAS No. 1392499-32-9

N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-PEG5-bromide is a PROTAC linker based on PEG and Alkyl/ether.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-Boc-PEG5-bromide
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-PEG5-bromide is a PROTAC linker based on PEG and Alkyl/ether.
  • Description
    N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-PEG5-bromide is a PROTAC linker based on PEG and Alkyl/ether.(In Vitro):ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ACSS2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1392499-32-9
  • Formula Weight
    400.3
  • Molecular Formula
    C15H30BrNO6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)OC(=O)NCCOCCOCCOCCOCCBr
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.?Dixon, Darryl David, et al. Benzimidazole derivatives as ACSS2 modulators and their preparation. WO2015175845A1
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