N-(5-Aminopentyl)acetamide

CAS No. 32343-73-0

N-(5-Aminopentyl)acetamide( Monoacetylcadaverine | N-Acetyl-15-pentanediamine | N-Acetylcadaverine )

Catalog No. M19992 CAS No. 32343-73-0

N-Acetylcadaverine is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large doses. N-(5-Aminopentyl)acetamide is a promising biochemical marker for cancer and many other pathophysiological conditions.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-(5-Aminopentyl)acetamide
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Acetylcadaverine is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large doses. N-(5-Aminopentyl)acetamide is a promising biochemical marker for cancer and many other pathophysiological conditions.
  • Description
    N-Acetylcadaverine is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large doses. N-(5-Aminopentyl)acetamide is a promising biochemical marker for cancer and many other pathophysiological conditions.
  • In Vitro
    Polyamine is a small organic polycation composed of a hydrocarbon backbone with multiple amino groups which ubiquitously exists in all living organisms from bacteria to higher animals. The critical step of polyamine biosynthesis generally includes the amino acid-decarboxylating reaction to produce the primary diamines, such as cadaverine from lysine. Synthesized polyamines are implicated in a wide variety of cytoplasmic reactions such as DNA replication and protein synthesis, and are essential for proper growth and proliferation of the organisms. Cadaverine is a linear molecule that terminate at both ends with an amine functional group. These functional groups confer to the molecules multiple positive charges at physiological pH. Cadaverine is produced through the action of basic amino acid decarboxylases and is found associated with the outer membrane.
  • In Vivo
    ——
  • Synonyms
    Monoacetylcadaverine | N-Acetyl-15-pentanediamine | N-Acetylcadaverine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    32343-73-0
  • Formula Weight
    144.21
  • Molecular Formula
    C7H16N2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 25 mg/mL
  • SMILES
    CC(=O)NCCCCCN
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Paik MJ et al. Urinary polyamines and N-acetylated polyamines in four patients with Alzheimer's disease as their N-ethoxycarbonyl-N-pentafluoropropionyl derivatives by gas chromatography-mass spectrometry in selected ion monitoring mode. Anal Chim Acta. 2006 Aug 18;576(1):55-60.
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