NP-G2-044

CAS No. 1807454-59-6

NP-G2-044( —— )

Catalog No. M23818 CAS No. 1807454-59-6

NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 61 In Stock
5MG 91 In Stock
10MG 135 In Stock
25MG 281 In Stock
50MG 426 In Stock
100MG 624 In Stock
500MG 1314 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NP-G2-044
  • Note
    Research use only, not for human use.
  • Brief Description
    NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
  • Description
    NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
  • In Vitro
    ——
  • In Vivo
    Animal Model:6-8 week old female BALB/c mice (mouse model bearing 4T1 tumor cells) Dosage:100 mg/kg Administration:I.p.; daily for 18 days Result:Inhibition of 4T1 mouse mammary tumor cell metastasis to the lung.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    fascin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1807454-59-6
  • Formula Weight
    399.37
  • Molecular Formula
    C21H16F3N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (250.39 mM; Need ultrasonic)
  • SMILES
    Cc(occ1)c1C(Nc1nn(Cc2ccc(C(F)(F)F)cc2)c2c1cccc2)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Han S, et al. Improving fascin inhibitors to block tumor cell migration and metastasis. Mol Oncol. 2016;10(7):966-980.
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