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NP-G2-044

CAS No. 1807454-59-6

NP-G2-044( —— )

Catalog No. M23818 CAS No. 1807454-59-6

NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 61 In Stock
5MG 91 In Stock
10MG 135 In Stock
25MG 281 In Stock
50MG 426 In Stock
100MG 624 In Stock
500MG 1314 In Stock
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Biological Information

  • Product Name
    NP-G2-044
  • Note
    Research use only, not for human use.
  • Brief Description
    NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
  • Description
    NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
  • In Vitro
    ——
  • In Vivo
    Animal Model:6-8 week old female BALB/c mice (mouse model bearing 4T1 tumor cells) Dosage:100 mg/kg Administration:I.p.; daily for 18 days Result:Inhibition of 4T1 mouse mammary tumor cell metastasis to the lung.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    fascin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1807454-59-6
  • Formula Weight
    399.37
  • Molecular Formula
    C21H16F3N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (250.39 mM; Need ultrasonic)
  • SMILES
    Cc(occ1)c1C(Nc1nn(Cc2ccc(C(F)(F)F)cc2)c2c1cccc2)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Han S, et al. Improving fascin inhibitors to block tumor cell migration and metastasis. Mol Oncol. 2016;10(7):966-980.
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