N-(2-Chloro-6-methylphenyl)-N-4-pyridinylurea
CAS No. 97627-24-2
N-(2-Chloro-6-methylphenyl)-N-4-pyridinylurea( —— )
Catalog No. M26317 CAS No. 97627-24-2
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 147 | In Stock |
|
10MG | 250 | In Stock |
|
25MG | 496 | In Stock |
|
50MG | 714 | In Stock |
|
100MG | 981 | In Stock |
|
500MG | 1971 | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameN-(2-Chloro-6-methylphenyl)-N-4-pyridinylurea
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NoteResearch use only, not for human use.
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Brief DescriptionN-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.
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DescriptionN-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.(In Vivo):N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg.?The activity seen with 30 mg/kg 37 is still present 4 h postdose.?Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol.?The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures.
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In Vitro——
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In VivoCompound shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg. The activity seen with 30 mg/kg 37 is still present 4 h postdose. Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol. The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures. Compound is selected for clinical trials.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptornAChR| PAFR
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Research Area——
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Indication——
Chemical Information
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CAS Number97627-24-2
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Formula Weight261.71
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Molecular FormulaC13H12ClN3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (477.63 mM)
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SMILESCc1cccc(Cl)c1NC(=O)Nc1ccncc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Synthesis and anti-platelet activity of ferulamide derivativesJournal of Chinese Pharmaceutical Sciences, 2002, 54(1):41-52.
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