N-(2-Chloro-6-methylphenyl)-N-4-pyridinylurea ( —— )

Catalog No. M26317 CAS No. 97627-24-2

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Product Name

N-(2-Chloro-6-methylphenyl)-N-4-pyridinylurea
Note

Research use only, not for human use.
Brief Description

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.
Description

N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures.(In Vivo):N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea shows anticonvulsant activity at 30 mg/kg in the initial tests with no signs of ataxia until 300 mg/kg.?The activity seen with 30 mg/kg 37 is still present 4 h postdose.?Compound is effective against seizures induced by maximal electroshock but does not protect mice from clonic seizures produced by the convulsant pentylenetetrazol.?The overall pharmacological profile suggests that Compound would be of therapeutic use in the treatment of generalized tonic-clonic and partial seizures.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

nAChR; PAFR
Research Area

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Indication

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1.Synthesis and anti-platelet activity of ferulamide derivativesJournal of Chinese Pharmaceutical Sciences, 2002, 54(1):41-52.

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