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MnTBAP chloride
CAS No. 55266-18-7
MnTBAP chloride( —— )
Catalog No. M35013 CAS No. 55266-18-7
MnTBAP chloride (Mn(III)TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 32 | In Stock |
|
| 25MG | 51 | In Stock |
|
| 50MG | 75 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMnTBAP chloride
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NoteResearch use only, not for human use.
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Brief DescriptionMnTBAP chloride (Mn(III)TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2.
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DescriptionMnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research.
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In Vitro——
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In VivoAnimal Model:C57BL/6J mice with 5/6 nephrectomy (Nx)Dosage:10?mg/kg Administration:IP; three times per week for twelve weeks Result:Attenuated renal fibrosis in 5/6 Nx mice and reduced protein expressions of fibronectin, collagen III in remnant kidneys.
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Synonyms——
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PathwayOthers
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TargetAntioxidant
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RecptorAntioxidant | NF-κB
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Research Area——
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Indication——
Chemical Information
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CAS Number55266-18-7
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Formula Weight876.13
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Molecular FormulaC48H25ClMnN4O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (113.75 mM; Ultrasonic )0.5 M NaOH : 20 mg/mL (22.75 mM; Ultrasonic)1M NaOH : 10 mg/mL (11.37 mM; ultrasonic and adjust pH to 8 with NaOH)
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SMILES[H+].O=C([O-])C=1C=CC(=CC1)C2=C3C=CC=4C(C=5C=CC(=CC5)C(=O)[O-])=C6C=CC7=C(C8=CC=C(C=C8)C(=O)[O-])C=9C=CC%10=C(C%11=CC=C(C=C%11)C(=O)[O-])C%12=CC=C2[N-]%12[Mn+3]([Cl-])([N]34)([N]%109)[N-]67
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jing Yu, et al. MnTBAP Therapy Attenuates Renal Fibrosis in Mice With 5/6 Nephrectomy. Oxid Med Cell Longev. 2016;2016:7496930.?
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