Mizolastine ( SL 85.0324; Mistalin; Mistamine; Mizolastina )

Catalog No. M10337 CAS No. 108612-45-9

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HNMR

HPLC

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Product Name

Mizolastine
Note

Research use only, not for human use.
Brief Description

Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.
Description

Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.
Synonyms

SL 85.0324; Mistalin; Mistamine; Mizolastina
Pathway

GPCR/G Protein
Target

Histamine Receptor
Recptor

H1 receptor
Research Area

Inflammation/Immunology
Indication

——

CAS Number

108612-45-9
Formula Weight

432.49
Molecular Formula

C24H25FN6O
Purity

>98%(HPLC)
Solubility

Ethanol: <1 mg/mL warmed (<1 mM); Water: <1 mg/mL (<1 mM); DMSO: <1 mg/mL (<1 mM)
SMILES

O=C1NC(N(C2CCN(C3=NC4=CC=CC=C4N3CC5=CC=C(F)C=C5)CC2)C)=NC=C1
Chemical Name

2-((1-(1-(p-Fluorobenzyl)-2-benzimidazolyl)-4-piperidyl)methylamino)-4(3H)-pyrimidinone

1.Brostoff J, et al.Allergy. 1996 May; 51(5):320-5.

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