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Mitoxantrone

CAS No. 65271-80-9

Mitoxantrone( mitozantrone )

Catalog No. M18958 CAS No. 65271-80-9

Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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50MG 42 In Stock
100MG 59 In Stock
200MG 98 In Stock
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Biological Information

  • Product Name
    Mitoxantrone
  • Note
    Research use only, not for human use.
  • Brief Description
    Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication.
  • Description
    Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    mitozantrone
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Topo II
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    65271-80-9
  • Formula Weight
    444.48
  • Molecular Formula
    C22H28N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 150 mg/mL; 337.47 mM
  • SMILES
    OCCNCCNc1ccc(NCCNCCO)c2c1C(=O)c1c(O)ccc(O)c1C2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bellosillo B, et al. Br J Haematol, 1998, 100(1), 142-146.
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