MitoBloCK-6

CAS No. 303215-67-0

MitoBloCK-6( —— )

Catalog No. M35338 CAS No. 303215-67-0

MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 31 Get Quote
10MG 45 Get Quote
25MG 70 Get Quote
50MG 116 Get Quote
100MG 177 Get Quote
200MG 267 Get Quote
500MG 464 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    MitoBloCK-6
  • Note
    Research use only, not for human use.
  • Brief Description
    MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.
  • Description
    MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    303215-67-0
  • Formula Weight
    357.23
  • Molecular Formula
    C19H14Cl2N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (139.97 mM)
  • SMILES
    Oc1c(Cl)cc(Cl)cc1\C=N\c1ccc(Nc2ccccc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92. ?
molnova catalog
related products
  • Benzyl selenocyanate

    Benzyl selenocyanate is a chemopreventive agent that effectively inhibits chemically induced tumors at both initiation and postinitiation stages in animal models.

  • NVS-CECR2-1

    NVS-CECR2-1 is a selective cat eye syndrome chromosome region candidate 2 (CECR2) inhibitor with antitumor activity and inhibits chromatin binding of CECR2 BRD. NVS-CECR2-1 is cytotoxic and can induce apoptosis.

  • GUT-70

    GUT-70 is a tricyclic coumarin derived from Calophyllum brasiliense, markedly reduces cell proliferation.