MitoBloCK-10

CAS No. 394694-98-5

MitoBloCK-10 ( 3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m )

Catalog No. M22749 CAS No. 394694-98-5

MitoBloCK-10 inhibits Tim44 binding to the precursor and to Hsp70.MitoBloCK-10 is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 144 Get Quote
10MG 216 Get Quote
25MG 357 Get Quote
50MG 529 Get Quote
100MG 767 Get Quote
500MG 1512 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    MitoBloCK-10
  • Note
    Research use only, not for human use.
  • Brief Description
    MitoBloCK-10 inhibits Tim44 binding to the precursor and to Hsp70.MitoBloCK-10 is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity.
  • Description
    MitoBloCK-10 inhibits Tim44 binding to the precursor and to Hsp70.MitoBloCK-10 is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity.
  • Synonyms
    3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    394694-98-5
  • Formula Weight
    293.28
  • Molecular Formula
    C12H8FN3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [O-][N+](=O)c1ccc(\C=N\NC(=O)c2cccc(F)c2)s1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Non Miyata, et al. Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44. J Biol Chem. 2017 Mar 31;292(13):5429-5442.
molnova catalog
related products
  • Praeruptorin C

    Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases.

  • PATULIN

    Patulin is a mycotoxin produced by a variety of molds commonly found in rotting apples including Aspergillus and Penicillium.

  • Elaiophylin

    Elaiophylin shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively.