Miriplatin

CAS No. 141977-79-9

Miriplatin( SM-11355 )

Catalog No. M17286 CAS No. 141977-79-9

Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 37 In Stock
10MG 51 In Stock
25MG 77 In Stock
50MG 104 In Stock
100MG 164 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Miriplatin
  • Note
    Research use only, not for human use.
  • Brief Description
    Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
  • Description
    Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
  • In Vitro
    Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.
  • In Vivo
    Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells.
  • Synonyms
    SM-11355
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    DNA Alkylator/Crosslinker
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    141977-79-9
  • Formula Weight
    764
  • Molecular Formula
    C34H68N2O4Pt
  • Purity
    >98% (HPLC)
  • Solubility
    DMF : < 1 mg/mL
  • SMILES
    [Pt+2].O=C([O-])CCCCCCCCCCCCC.N[C@@H]1CCCC[C@H]1N.[O-]C(=O)CCCCCCCCCCCCC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ishikawa T, et al. Predictive factor of local recurrence after balloon-occluded TACE with miriplatin (MPT) in hepatocellular carcinoma. PLoS One. 2014 Jul 21;9(7):e103009.
molnova catalog
related products
  • Propionylpromazine h...

    Propionylpromazine hydrochloride is a dopamine receptor D2 (DRD2) antagonist.

  • Ro 10-5824 dihydroch...

    Ro 10-5824 dihydrochloride is a selective agonist of dopamine D4 receptor partial, (Ki of 5.2 nM).

  • BL-1020

    BL-1020 is an ester of GABA and perphenazine, fuctions as orally-active antipsychotic agent and acts as a D2 antagonist and GABA agonist.