Minoxidil

Research use only, not for human use.

Minoxidil(U 10858) is an antihypertensive vasodilator medication.

Minoxidil(U 10858) is an antihypertensive vasodilator medication.(In Vitro):Minoxidil (1-00 μM; 24 hours; RAMEC cells) treatment shows very low cytotoxicities in the whole area of concentrations examined (from 1 μM to 100 μM).(In Vivo):Minoxidil (0.01 mmoL/kg body weight; intraperitoneal injection; for 3.5 hours; fisher 344 rats) treatment inhibits carrageenan-induced rat paw oedema with an inhibitory potency (49%).

Minoxidil (1-00 μM; 24 hours; RAMEC cells) treatment shows very low cytotoxicities in the whole area of concentrations examined (from 1 μM to 100 μM).

Minoxidil (0.01 mmoL/kg body weight; intraperitoneal injection; for 3.5 hours; fisher 344 rats) treatment inhibits carrageenan-induced rat paw oedema with an inhibitory potency (49%). Animal Model:Fisher 344 rats (150-200 g) with oedema Dosage:0.01 mmol/kg body weight Administration:Intraperitoneal injection; for 3.5 hours Result:Inhibition of the carrageenin-induced oedema.

Loniten | U-10858

Chromatin/Epigenetic

COX

COX-1| Potassium Channel

Cardiovascular Disease

——

38304-91-5

209.25

C9H15N5O

>98% (HPLC)

DMSO: 0.25 mg/mL 1.19 mM

NC1=CC(N2CCCCC2)=NC(N1O)=N

3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

(-20℃)

With Ice Pack

≥ 2 years