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Apyramide
CAS No. 68483-33-0
Apyramide( —— )
Catalog No. M32784 CAS No. 68483-33-0
Apyramide is an anti-inflammatory agent (NSAID) that acts as a prodrug of indomethacin, a potent, blood-brain permeable, and nonselective inhibitor of COX1 and COX2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
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| 5MG | 39 | In Stock |
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| 10MG | 68 | In Stock |
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| 25MG | 119 | In Stock |
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| 50MG | 170 | In Stock |
|
| 100MG | 231 | In Stock |
|
| 200MG | 316 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameApyramide
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NoteResearch use only, not for human use.
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Brief DescriptionApyramide is an anti-inflammatory agent (NSAID) that acts as a prodrug of indomethacin, a potent, blood-brain permeable, and nonselective inhibitor of COX1 and COX2.
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DescriptionApyramide is an anti-inflammatory agent (NSAID) and behaves as a proagent of indomethacin (HY-14397). Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2.
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In Vitro——
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In VivoApyramide is far less toxic than indomethacin in rats and mice by the oral or the i.p. route. It exhibits anti-inflammatory activity on carrageenin-induced paw oedema, cotton pellet granuloma and adjuvant arthritis, as well as analgesic and antipyretic activities.
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX
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Research Area——
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Indication——
Chemical Information
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CAS Number68483-33-0
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Formula Weight490.93
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Molecular FormulaC27H23ClN2O5
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Purity>98% (HPLC)
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Solubility——
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SMILESC(=O)(N1C=2C(C(CC(OC3=CC=C(NC(C)=O)C=C3)=O)=C1C)=CC(OC)=CC2)C4=CC=C(Cl)C=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sauvaire D, et al. Pharmacological activity and toxicity of apyramide: comparison with non-steroidal anti-inflammatory agents. Drugs Exp Clin Res. 1987;13(5):247-52.?
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