Cart
sales@molnova.com
Mevociclib
CAS No. 1816989-16-8
Mevociclib ( SY-1365 )
Catalog No. M26471 CAS No. 1816989-16-8
Mevociclib is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 262 | Get Quote |
|
| 50MG | 1485 | Get Quote |
|
| 100MG | 2520 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMevociclib
-
NoteResearch use only, not for human use.
-
Brief DescriptionMevociclib is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.
-
DescriptionMevociclib is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.
-
SynonymsSY-1365
-
PathwayAngiogenesis
-
TargetCDK
-
RecptorAkt; caspase-3; JNK1; p44/42 MAPK; RhoGDI
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1816989-16-8
-
Formula Weight587.1
-
Molecular FormulaC31H35ClN8O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@@]1(C)CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kohno K, Ohashi E, et al. Anti-inflammatory effects of adenosine N1-oxide. J Inflamm (Lond). 2015 Jan 20;12(1):2.
molnova catalog
related products
-
CID44216842
CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor.?
-
THZ-1 hydrochloride
THZ-1 hydrochloride is a potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM; also weakly inhibits CDK12 with IC50 of 250 nM.
-
AT-7519
A potent CDK2 inhibitor with IC50 of 47 nM; also inhibits CDK1/4/5 with IC50 of 190/67/18 nM and shows selectivity over some kinases (Aurora A, IR kinase, MEK, PDK1, c-Abl, IC50>10 uM).
