Methylproamine

Research use only, not for human use.

Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.

Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.(In Vitro):Immunocytochemical methods were used to measure the accumulation of phosphorylated H2AX (γH2AX) foci following ionizing radiation (IR) in patient-derived lymphoblastoid cells exposed to methylproamine. Pulsed field gel electrophoresis DNA damage and repair assays were performed to directly interrogate the action of methylproamine on DNA in irradiated cells.Methylproamine-treated cells had fewer γH2AX foci after IR compared to untreated cells. Also, the presence of methylproamine decreased the amount of lower molecular weight DNA entering the gel.

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Others

Other Targets

α2 adrenergic receptor

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188247-01-0

465.6

C28H31N7

>98% (HPLC)

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CN(C)c1ccc(-c2nc3ccc(cc3[nH]2)-c2nc3ccc(cc3[nH]2)N2CCN(C)CC2)c(C)c1

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(-20℃)

With Ice Pack

≥ 2 years