NS-2028
CAS No. 204326-43-2
NS-2028 ( —— )
Catalog No. M23914 CAS No. 204326-43-2
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 73 | In Stock |
|
5MG | 120 | In Stock |
|
10MG | 219 | In Stock |
|
25MG | 447 | In Stock |
|
50MG | 669 | In Stock |
|
100MG | 945 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameNS-2028
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NoteResearch use only, not for human use.
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Brief DescriptionNS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity).
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DescriptionNS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase (IC50: 17 nM and 20 nM). NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells (IC50: 30 nM). NS-2028 inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 μM). NS-2028 decreases vascular endothelial growth factor-induced angiogenesis and permeability.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorsGC
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Research Area——
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Indication——
Chemical Information
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CAS Number204326-43-2
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Formula Weight269.1
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Molecular FormulaC9H5BrN2O3
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Purity>98% (HPLC)
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SolubilityDMSO: 250 mg/mL (929.20 mM; Need ultrasonic)
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SMILESO=C1ON=C2COC3=CC=C(Br)C=C3N21
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Olesen SP, et al. Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase. Br J Pharmacol. 1998 Jan;123(2):299-309.
molnova catalog
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