Methoprene

CAS No. 40596-69-8

Methoprene( ZR-515 )

Catalog No. M26753 CAS No. 40596-69-8

Methoprene is a juvenile hormone (JH) mimic and a biological pesticide.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Methoprene
  • Note
    Research use only, not for human use.
  • Brief Description
    Methoprene is a juvenile hormone (JH) mimic and a biological pesticide.
  • Description
    Methoprene is a juvenile hormone (JH) mimic and a biological pesticide. Methoprene acts as an insect growth regulator interfering with the lifecycles of insects and preventing insects from reaching maturity or reproducing.(In Vivo):The time of first brood deposition is affected by methoprene, with a clear concentration-dependent response and a NOEC of 32 nM. Methoprene reduces fecundity according to a 2-segmented line, with thresholds of 24 and < or =0.18 nM. Methoprene reduces the growth rate of daphnids with evidence of only a single concentration-response line, having a threshold of 12.6 nM. Molt frequency is reduced by methoprene in a concentration-dependent manner, with a response curve corresponding to a 2-segmented line and thresholds at 4.2 and 0.21 nM.
  • In Vitro
    Methoprene reduces the growth rate of daphnids with evidence of only a single concentration-response line, having a threshold of 12.6 nM. Molt frequency is reduced by methoprene in a concentration-dependent manner, with a response curve corresponding to a 2-segmented line and thresholds at 4.2 and 0.21 nM. An endpoint related to reproductive maturation, the time of first brood deposition, is also affected by methoprene, with a clear concentration-dependent response and a NOEC of 32 nM. Methoprene reduces fecundity according to a 2-segmented line, with thresholds of 24 and < or =0.18 nM. Methoprene elicits significant toxicity to endocrine-related processes in the 5-50 nM concentration range.
  • In Vivo
    ——
  • Synonyms
    ZR-515
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    E3 Ligase Ligand-Linker Conjugate
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    40596-69-8
  • Formula Weight
    310.478
  • Molecular Formula
    C19H34O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethanol : 100 mg/mL (322.09 m)
  • SMILES
    COC(C)(C)CCCC(C)C\C=C\C(\C)=C\C(=O)OC(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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